Monday, 15 January 2007

More mechanisms for tumour promotion

In our book we explain how one's emotional state may impact on the components of tumour surveillance and suppression. Now we find that further details of a mechanism which promotes metastasis - the formation of further tumours - have been discovered by researchers at Ohio State University. Receptors for norepinephrine (noradrenalin) allow the hormone to act on some tumour cells to produce two compounds which can break down the tissue around these cells and allow them to migrate into the bloodstream. Norepinephrine also stimulate the tumour cells to release another compound that promotes the growth of new blood vessels that feed cancer cells, speeding up tumour growth.

Norepinephrine is one of the so-called 'stress' hormones, whose levels may be expected to rise in emotionally difficult times.

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